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GSTA1 Protein, Human, Recombinant (His)
Catalog Number: orb1959030
| Catalog Number | orb1959030 |
|---|---|
| Category | Proteins |
| Description | GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy. |
| Tag | C-His |
| Purity | 92.10% |
| UniProt ID | P08263 |
| MW | 27.1 kDa (predicted) |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expression System | HEK293 Cells |
| Biological Origin | Human |
| Biological Activity | GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy. |
| Expression Region | A DNA sequence encoding the human GSTA1 (NP_665683.1) (Met1-Phe222) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Met |
| Storage | -20°C |
| Note | For research use only |
Recombinant Human GSTA1 Protein, N-His [orb2836588]
> 90% as determined by SDS-PAGE.
27.81 kDa
100 μg, 50 μg, 20 μg
