GSK-114

• Catalog Number: orb1305989
• Category: Small Molecules
• Description: GSK-114
• Purity: 99.66%
• MW: 417.48
• Biological Activity: GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.
• CAS Number: [1301761-96-5]
• Formula: C₁₉H₂₃N₅O₄S
• SMILES: CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1
• Storage: -20°C
• Note: For research use only