GSDMD Rabbit Polyclonal Antibody

SKU: orb183073

Description

GSDMD Rabbit Polyclonal Antibody

Images & Validation

• Tested Applications: WB
• Dilution range: WB=1:500-2000
• Reactivity: Human
• Predicted Reactivity: Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human GSDMD (31-150/484aa)
• Target: GSDMD
• Molecular Weight: 32/53 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

DF 5L; DF5L; DFNA 5L; DFNA5L; FKSG 10; FKSG10; FLJ12150; Gasdermin D; Gasdermin domain containing 1; Gasdermin domain containing protein 1; Gasdermin domain-containing protein 1; Gasdermin-D; GasderminD; GSDMD_HUMAN; GSDMDC 1; GSDMDC1; Gasdermin-D, N-terminal; GSDMD-NT; hGSDMD-NTD; Gasdermin-D, C-terminal; GSDMD-CT; hGSDMD-CTD.

Sample: Lane 1: Human Huvec cell lysates, Lane 2: Human A431 cell lysates, Lane 3: Human Hela cell lysates, Primary: Anti-GSDMD (orb183073) at 1/1000 dilution, Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution, Predicted band size: 53 kDa, Observed band size: 59 kDa.

Quick Database Links

Gene Symbol

GSDMD

UniProt

P57764

References

Jing Li 1, Yubing Yang 1, Chenguang Zhao 2, Jinghao Zhao 1, Xiaohui Wang 3, Shengshou Ye 4, Dong Wang 1, Chengdong Zhou 1, Jie Li 5, Shuang Wang 5, Ke Li 1, Chunmiao Liu 1, Xijing He 1 6, Jie Qin Microglial C/EBPβ-Fcgr1 regulatory axis blocking inhibits microglial pyroptosis and improves neurological recovery J Neuroinflammation, (2025)

PubMed: 39891259