GIRK2 Antibody / KCNJ6

• Catalog Number: orb1824082
• Category: Antibodies
• Description: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: KCNJ6/7559
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Mouse IgG2, kappa
• Immunogen: A recombinant fragment of human KCNJ6 protein was used as the immunogen for the GIRK2 antibody.
• Antibody Type: Primary Antibody
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This GIRK2 antibody is available for research use only.
• UniProt ID: P48051
• Storage: Aliquot the GIRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

IHC staining of FFPE human brain tissue with GIRK2 antibody (clone KCNJ6/7559) at 2 ug/ml. HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free GIRK2 antibody (clone KCNJ6/7559) as confirmation of integrity and purity.