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Catalog Number | orb1824080 |
---|---|
Category | Antibodies |
Description | This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015] |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | KCNJ6/7559 |
Tested applications | IHC-P |
Reactivity | Human |
Isotype | Mouse IgG2, kappa |
Immunogen | A recombinant fragment of human KCNJ6 protein was used as the immunogen for the GIRK2 antibody. |
Antibody Type | Primary Antibody |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
Conjugation | Unconjugated |
Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
Hazard Information | This GIRK2 antibody is available for research use only. |
UniProt ID | P48051 |
Storage | Aliquot the GIRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IHC staining of FFPE human brain tissue with GIRK2 antibody (clone KCNJ6/7559) at 2 ug/ml. HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free GIRK2 antibody (clone KCNJ6/7559) as confirmation of integrity and purity.