GDNF (C) Antibody, Rabbit Polyclonal

SKU: orb66950

Description

Rabbit polyclonal to GDNF.Glial cell line-derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor, which promotes the survival and differentiation of dopaminergic neurons, and prevents apoptosis of motor neurons induced by axotomy. GDNF is processed to a mature secreted form that exists as a homodimer, which is a ligand for the product of the RET earranged during transfection) proto-oncogene. Defects in GDNF may be associated with Hirschsprung's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). GDNF also regulates kidney development, spermatogenesis and alcohol consumption.

Research Area

Epigenetics, Neuroscience

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human GDNF
• Molecular Weight: 24
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-GDNF antibody,anti-Glial cell linederived neurotrophic factor antibody,anti-Astrocytederived trophic factor antibody,anti-ATF antibody

Western blot analysis of total cell extracts from mouse brain using GDNF antibody

Quick Database Links

UniProt

P39905