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Catalog Number | orb66950 |
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Category | Antibodies |
Description | Rabbit polyclonal to GDNF.Glial cell line-derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor, which promotes the survival and differentiation of dopaminergic neurons, and prevents apoptosis of motor neurons induced by axotomy. GDNF is processed to a mature secreted form that exists as a homodimer, which is a ligand for the product of the RET earranged during transfection) proto-oncogene. Defects in GDNF may be associated with Hirschsprung's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). GDNF also regulates kidney development, spermatogenesis and alcohol consumption. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse |
Immunogen | C-terminal region of human GDNF |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 24 |
UniProt ID | P39905 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-GDNF antibody,anti-Glial cell linederived neu Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from mouse brain using GDNF antibody