GCLM Antibody / Glutamate-Cysteine Ligase Regulatory Subunit

• Catalog Number: orb699488
• Category: Antibodies
• Description: GCLM, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: CPTC-GCLM-1
• Tested applications: IHC-P, WB
• Reactivity: Human
• Isotype: Mouse IgG2a, kappa
• Immunogen: Recombinant human full-length GCLM protein was used as the immunogen for the GCLM antibody.
• Dilution range: Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This GCLM antibody is available for research use only.
• UniProt ID: P48507
• Storage: Store the GCLM antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the GCLM antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.