FXR antibody

• Catalog Number: orb156973
• Category: Tools
• Description: FXR antibody
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: FC, WB
• Predicted Reactivity: Bovine, Canine, Equine, Porcine, Rat, Sheep
• Reactivity: Human, Mouse
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human FXR/Bile Acid Receptor NR1H4 (175-280/486 aa)
• Concentration: 1mg/ml
• Dilution range: WB=1:500-2000, Flow-Cyt=3ug/test, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• MW: 56 kDa
• Target: NR1H4
• UniProt ID: Q96RI1
• Storage: Shipped at 4°C. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
• Buffer/Preservatives: 0.01M TBS(pH7.4) with 1% rAlbumin, 0.03% Proclin300 and 50% Glycerol.
• Alternative names: Bile Acid Receptor NR1H4; BAR; FXR; Farnesoid X ac
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Huang, Fengjie et al. Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism Nat Commun, 10, 4971 (2019)

PubMed: 31672964

Applications

WB

Reactivity

Mouse

Alam, Gulzar et al. Activation of farnesoid X receptor (FXR) induces crystallin zeta expression in mouse medullary collecting duct cells Pflugers Arch, 472, 1631-1641 (2020)

PubMed: 32914211

Applications

WB

Reactivity

Mouse

Western blot analysis of human hepG2 lysates using FXR antibody.

Western blot analysis of mouse large intestine lysate tissue using FXR antibody.

Western blot analysis of mouse liver lysate tissue using FXR antibody.

Flow cytometric analysis of A549 cells using FXR antibody

Western blot analysis of hepG2 cell (human) lysate tissue using FXR antibody

Western blot analysis of mouse liver lysate tissue using FXR antibody.