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Description
Research Area
Metabolism Research
Images & Validation
−
Item 1 of 1
| Tested Applications | ELISA, WB |
|---|---|
| Dilution Range | WB:1:500:5000 |
| Reactivity | Human |
Key Properties
−| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human Folylpolyglutamate synthase, mitochondrial protein (443-546AA) |
| Target | FPGS |
| Purification | >95%, Protein G purified |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−EC 6.3.2.17 antibody; FOLC antibody; FOLC_HUMAN antibody; Folylpoly gamma glutamate synthetase antibody; Folylpoly-gamma-glutamate synthetase antibody; Folylpolyglutamate synthase antibody; Folylpolyglutamate synthase mitochondrial antibody; FPGS antibody; mitochondrial antibody; OTTHUMP00000022201 antibody; OTTHUMP00000022202 antibody; Tetrahydrofolate synthase antibody; Tetrahydrofolylpolyglutamate synthase antibody
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Quick Database Links
Gene Symbol
FPGS
UniProt
UniProt Details
− No UniProt data available
Protocol Information
WB
Western Blot (IB, immunoblot)
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
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Felix van der Krift,Dick W Zijlmans, Rhythm Shukla , Ali Javed , Panagiotis I Koukos, Laura LE Schwarz ,Elpetra PM Timmermans-Sprang , Peter EM Maas , Digvijay Gahtory, Maurits van den Nieuwboer, Jan A Mol ,Ger J Strous , Alexandre MJJ Bonvin , Mario van der Stelt, Edwin JA Veldhuizen , Markus Weingarth ,Michiel Vermeulen , Judith Klumperman , Madelon M Maurice A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance Life Sci Alliance, 6(11), e202302058 (2023)
Applications
WB
Reactivity
Human
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