FPGS Antibody

• Catalog Number: orb422877
• Category: Antibodies
• Description: This FPGS Antibody is an unconjugated polyclonal product. It tagets FPGS using a Recombinant Human Folylpolyglutamate synthase, mitochondrial protein (443-546AA) as the immunogen. This antibody is suitable for ELISA, WB. Purification: >95%, Protein G purified.
• Target: FPGS
• Clonality: Polyclonal
• Species/Host: Rabbit
• Isotype: IgG
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Liquid
• Buffer/Preservatives: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol
• Purification: >95%, Protein G purified
• Immunogen: Recombinant Human Folylpolyglutamate synthase, mitochondrial protein (443-546AA)
• UniProt ID: Q05932
• Tested applications: ELISA, WB
• Dilution range: WB:1:500:5000
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: EC 6.3.2.17 antibody; FOLC antibody; FOLC_HUMAN an
• Research Area: Signal Transduction
• Note: For research use only

References

Felix van der Krift,Dick W Zijlmans, Rhythm Shukla , Ali Javed , Panagiotis I Koukos, Laura LE Schwarz ,Elpetra PM Timmermans-Sprang , Peter EM Maas , Digvijay Gahtory, Maurits van den Nieuwboer, Jan A Mol ,Ger J Strous , Alexandre MJJ Bonvin , Mario van der Stelt, Edwin JA Veldhuizen , Markus Weingarth ,Michiel Vermeulen , Judith Klumperman , Madelon M Maurice A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance Life Sci Alliance, 6(11), e202302058 (2023)

PubMed: 37591722

Applications

WB

Reactivity

Human

Western blot aanalysis of HepG2 whole cell lysate, MCF-7 whole cell lysateusing FPGS antibody