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Catalog Number | orb80166 |
---|---|
Category | Proteins |
Description | Exendin 4 Recombinant is novel 39-amino acids peptide having a molecular mass of 4186.7 Dalton, which shares 53%, sequence homology with GLP-17-36 amide and interacts with the same membrane receptor. The Exendin-4 is purified by proprietary chromatographic techniques. |
Tested applications | SDS-PAGE |
Purity | > 95.0% as determined by RP-HPLC and analysis by SDS-PAGE |
Conjugation | Unconjugated |
Target | Exendin 4 |
Solubility (25°C) | It is recommended to reconstitute the lyophilized Exendin Recombinant in sterile H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. |
Protein Sequence | The sequence determined and was found to be His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser. |
Biological Origin | E.coli |
Biological Activity | 1. Regulates Glucose levels rapidly2. Reduces Insulin resistence 3. Reduces Glucagon4. Reduces HbA1c5. Stimulates beta cell growth which stimulates insulin production. |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | The Exendin-4 peptide was lyophilized after extensive dialyses against 20 mM PBS and contains 4% mannitol. |
Alternative names | Exenatide protein Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Exendin 4 protein
99.72% | |
141758-74-9 | |
4186.57 | |
C184H282N50O60S |
Greater than 99.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
Greater than 96.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | |
Escherichia Coli |
99.92% | |
4063.46 | |
C179H277N47O59S |