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Catalog Number | orb2635966 |
---|---|
Category | Antibodies |
Description | The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk). |
Clonality | Recombinant |
Species/Host | Rabbit |
Isotype | Rabbit IgG, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | A recombinant fragment (within amino acids 1-200) of human EPHB4 protein was used as the immunogen for the recombinant EPH Receptor B4 antibody. |
UniProt ID | P54760 |
Tested applications | IHC-P |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml |
Application notes | Optimal dilution of the recombinant EPH Receptor B4 antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | EPHB4/9663R |
Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This recombinant EPH Receptor B4 antibody is available for research use only. |
Note | For research use only |
IHC staining of FFPE human liver tissue with recombinant EPH Receptor B4 antibody (clone EPHB4/9663R). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant EPH Receptor B4 antibody (clone EPHB4/9663R) as confirmation of integrity and purity.