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Catalog Number | orb1732692 |
---|---|
Category | Antibodies |
Description | EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 5E9 |
Tested applications | IP, WB |
Reactivity | Human |
Isotype | Mouse IgG1 |
Immunogen | Synthetic Peptide of EGFR |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000 |
Conjugation | Unconjugated |
MW | Calculated MW: 134 kDa; Observed MW: 170 kDa |
Entrez | 1956 |
UniProt ID | P00533 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | EGFR; ERBB; ERBB1; HER1; Epidermal growth factor r Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA, ICC, IF, IHC-P, WB | |
Human, Mouse, Porcine, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, FC, ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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