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Catalog Number | orb147959 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal to DUX4 (HRP). DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues.. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | P2B1 |
Tested applications | ICC, IHC, WB |
Reactivity | Human, Mouse |
Isotype | IgG1 |
Immunogen | C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag |
Concentration | 1 mg/ml |
Dilution range | WB (1:1000), ICC/IF (1:1000) |
Conjugation | HRP |
MW | 45kDa |
Target | DUX4 |
Entrez | 22947 |
UniProt ID | F5GZ66 |
NCBI | NP_149418.3 |
Storage | Conjugated antibodies should be stored at 4°C |
Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated |
Alternative names | Double homeobox 4 antibody, Double homeobox 10 ant Read more... |
Note | For research use only |
Application notes | 1 µg/ml of SMC-192 was sufficient for detection of DUX4 in 20 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary. |
Expiration Date | 12 months from date of receipt. |
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