DUX4 antibody

• Catalog Number: orb147958
• Category: Antibodies
• Description: Mouse monoclonal to DUX4 (FITC). DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: P2B1
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse
• Isotype: IgG1
• Immunogen: C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000), ICC/IF (1:1000)
• Conjugation: FITC
• MW: 45kDa
• Target: DUX4
• Entrez: 22947
• UniProt ID: F5GZ66
• NCBI: NP_149418.3
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: Double homeobox 4 antibody, Double homeobox 10 ant
• Note: For research use only
• Application notes: 1 µg/ml of SMC-192 was sufficient for detection of DUX4 in 20 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
• Expiration Date: 12 months from date of receipt.