Donafenib (Sorafenib D3)

• Catalog Number: orb1089591
• Category: Small Molecules
• Description: Sorafenib D3 (Bay 43-9006 D3) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 15 nM, 20 nM and 22 nM for Raf-1, mVEGFR-2, mVEGFR-3 and B-RAF, respectively.
• CAS Number: [1130115-44-4]
• MW: 467.8434391
• SMILES: [2H]C(NC(C1=NC=CC(OC2C=CC(NC(NC3C=CC(Cl)=C(C(F)(F)F)C=3)=O)=CC=2)=C1)=O)([2H])[2H]
• Formula: C₂₁H₁₆CLF₃N₄O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.