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DMAP1 (C) Antibody, Rabbit Polyclonal

Catalog Number: orb67071

DispatchUsually dispatched within 5-10 working days.
$ 440.00
Catalog Numberorb67071
CategoryAntibodies
DescriptionRabbit polyclonal to DMAP1.DNA methyltransferase 1-associated protein 1 (DMAP1) is a subunit of several distinct complexesinvolved in the repression or activation of transcription. DMAP1 can independently represstranscription and is targeted to replication foci throughout S phase by interacting directly with the Nterminusof DNA methyltransferase 1 (DNMT1). During late S phase, histone deacetylase 2 (HDAC2)is added to this complex, providing a means to deacetylate histones in transcriptionally inactiveheterochromatin following replication. DMAP1 is also a component of the nucleosomeacetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibilitygene 101 and the pro-apoptotic death-associated protein 6, among others.
Species/HostRabbit
ClonalityPolyclonal
Tested applicationsWB
ReactivityHuman
ImmunogenC-terminal region of human DMAP1
Dilution rangeWB:1:1000-1:5000
PurityAffinity purification
ConjugationUnconjugated
MW53
UniProt IDQ9NPF5
Storage-20°C
Buffer/Preservatives0.01% NaN3
Alternative namesanti-DMAP1 antibody,anti-DNA methyltransferase 1as
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NoteFor research use only
Expiration Date12 months from date of receipt.
DMAP1 (C) Antibody, Rabbit Polyclonal

Western blot analysis of total cell extracts from human Hela using DMAP1 antibody