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Catalog Number | orb1961338 |
---|---|
Category | Proteins |
Description | Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. |
Tag | C-6xHis |
Purity | 99.22% |
MW | 42 KDa (reducing condition) |
UniProt ID | P49366 |
Protein Sequence | Met1-Asp369 |
Expression System | E. coli |
Biological Origin | Human |
Biological Activity | Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. |
Expression Region | Met1-Asp369 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human DHPS(Met1-Asp369) was fused with the C-terminal His Tag and expressed in E. coli. |