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Catalog Number | orb1961631 |
---|---|
Category | Small Molecules |
Description | DEFB4A Protein, Human, Recombinant |
Purity | 98.00% |
MW | 9 KDa, reducing conditions |
Biological Activity | β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Greater than 90% as determined by SDS-PAGE. | |
31.3 kDa | |
E.coli |
ELISA, MS, SDS-PAGE, WB | |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. | |
E. coli |
Greater than 90% as determined by SDS-PAGE. | |
31.3 kDa | |
E.coli |
Greater than 90% as determined by SDS-PAGE. | |
31.3 kDa | |
E.coli |
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