DAPM

SKU: orb2566522

Description

DAPM (gamma-Secretase Inhibitor XVI) is a small molecule Notch pathway inhibitor with demonstrated anticancer and antiproliferative activity. It suppresses Notch signaling, upregulates KLF4 and p21 expression in human colon cancer cells in vitro, and has been applied in research models such as renal tubular adenomas.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 208255-51-0
• MW: 390.38
• Purity: 99.76%
• Formula: C₂₀H₂₀F₂N₂O₄
• SMILES: [C@@H](NC([C@@H](NC(CC1=CC(F)=CC(F)=C1)=O)C)=O)(C(OC)=O)C2=CC=CC=C2
• Target: Gamma-secretase

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DAPM, N-[N-3,5-Difluorophenacetyl]-L-alanyl-S-phenylglycine Methyl Ester, gamma-Secretase Inhibitor XVI, γ-Secretase Inhibitor XVI

Compound Identifiers

PubChem CID

10452973