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| Catalog Number | orb511246 |
|---|---|
| Category | Proteins |
| Description | Cynomolgus IGF-I R, His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Asn 932 (Accession # G7P9I7-1). |
| Target | IGF-I R / IGF-1 R |
| Conjugation | Unconjugated |
| Tag | C-10×His |
| Reactivity | Monkey |
| Form/Appearance | Powder |
| Buffer/Preservatives | PBS, pH 7.4 |
| Purity | 90% |
| UniProt ID | G7P9I7 |
| MW | 104.9 kDa |
| Application notes | This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin convertase cleavage site, 737-RKRR-740, and will be partially processed into N (α chain) and C-terminal fragment (partial β chain) with calculated MW of 81.1 kDa and 23.8 kDa respectively. The protein migrates as 45-50 kDa (partial β chain), 96-115 kDa (α chain) and 120 kDa (α chain & partial β chain) under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expression System | HEK293 |
| Endotoxins | 1.0 EU per μg |
| Expression Region | Glu 31 - Asn 932 |
| Storage | -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower |
| Research Area | Disease Biomarkers |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |

Immobilized Cynomolgus IGF-I R, His Tag (Cat. No. orb511246) at 5 μg/mL (100 μL/well) can bind Human IGF-I, Fc Tag (Cat. No. orb257564) with a linear range of 5-78 ng/mL (QC tested).
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