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CTOP

SKU: orb1679301

Description

This small molecule is a potent and selective μ-opioid receptor antagonist (Ki μ=0.96 nM, δ>10,000 nM). Upon central administration in vivo, it induces behavioral effects. In vitro, it also enhances potassium currents in rat locus coeruleus neurons through a mechanism independent of the μ receptor.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetOpioid Receptor
Molecular Weight1062.28

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

CTOP (orb1679301)

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