CTAP

SKU: orb1679303

Description

This highly potent and selective μ opioid receptor antagonist exhibits an IC50 of 3.5 nM with over 1200-fold selectivity for δ opioid and somatostatin receptors. Its brain-penetrant properties make it a valuable pharmacological tool for in vivo studies of pain, addiction, and reward pathways, as well as for in vitro receptor characterization.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Opioid Receptor
• CAS Number: 103429-32-9
• MW: 1104.32
• Formula: C₅₁H₆₉N₁₃O₁₁S₂
• SMILES: C[C@@H](O)[C@H](NC(=O)C1NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90479802