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Catalog Number | orb1732780 |
---|---|
Category | Antibodies |
Description | The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 3D10 |
Tested applications | WB |
Reactivity | Human |
Isotype | Mouse IgG2b |
Immunogen | Purified recombinant human CrkII protein fragments expressed in E.coli. |
Concentration | 1mg/ml |
Dilution range | WB: 1/500-1/1000 |
Conjugation | Unconjugated |
MW | Calculated MW: 34 kDa; Observed MW: 34 kDa |
Entrez | 1398 |
UniProt ID | P46108 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | Adapter molecule crk; avian sarcoma virus CT10 (v- Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
FC, WB | |
Human, Mouse | |
Monoclonal | |
Unconjugated |
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