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Catalog Number | orb106556 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal antibody to Cleaved-caspase 3 |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | IF, IHC-P, WB |
Reactivity | Human, Mouse, Rat |
Immunogen | A synthesized peptide derived from human CASP3, corresponding to amino acid residues 163-182aa |
Dilution range | WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500 |
Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol |
Purity | The antiserum was purified by peptide affinity chromatography |
Conjugation | Unconjugated |
MW | 17kDa; 32kD(Calculated) |
Storage | Stable for 12 months from date of receipt. Store at -20 °C. Stable for 12 months from date of receipt |
Alternative names | anti Apopain antibody, anti CASP 3 antibody, anti Read more... |
Background | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Wang, Weiwei et al. Notoginsenoside R1 alleviates high glucose-evoked damage in RSC96 cells through down-regulation of miR-503 Artif Cells Nanomed Biotechnol, 47, 3947-3954 (2019)
Chen, Huaxia et al. Circ_0008450 downregulates Runx3 to promote the proliferation and epithelial-mesenchymal transition of human keratinized epithelial cells Cell Cycle, 19, 3303-3316 (2020)
Yang, Xifeng et al. Downregulation of miR‑181b inhibits human colon cancer cell proliferation by targeting CYLD and inhibiting the NF‑κB signaling pathway Int J Mol Med, 46, 1755-1764 (2020)
Jin, Yunfeng et al. SNAI2 promotes the development of ovarian cancer through regulating ferroptosis Bioengineered, 13, 6451-6463 (2022)
D'Onofrio, Nunzia et al. ROS-Mediated Apoptotic Cell Death of Human Colon Cancer LoVo Cells by Milk δ-Valerobetaine Sci Rep, 10, 8978 (2020)
Immunohistochemical analysis of formalin-fixed and paraffin embedded ehrlich ascites carcinoma tissue using caspase3 antibody at 1:100 dilution [Reviews]
Western blot analysis of extracts from COLO cells using Cleaved-caspase 3 antibody
IHC-P, WB | |
Human, Mouse, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
FC, IHC-P, WB | |
Canine, Rabbit, Rat | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
FC, IHC-P, WB | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, IHC-P, WB | |
Human, Mouse | |
Polyclonal | |
Unconjugated |
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