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Product Overview
Product Name Claudin 1 antibody
Catalog Number orb10447
Species/HostRabbit
ReactivityHuman, Mouse, Porcine, Rat
ConjugationUnconjugated
Tested applicationsIHC-P, P-ELISA, WB
Immunogen KLH conjugated synthetic peptide derived from human Claudin 1. Please contact us for the exact immunogen sequence. The peptide is available as orb374718.
Target Claudin 1
Alternative Names
Product Properties
Form/Appearance 10 mM PBS, 0.02% sodium azide
Concentration - 100 μg (in 200 μl): 0.5 mg/ml
- 200 μg (in 400 μl): 0.5 mg/ml
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Isotype IgG
ClonalityPolyclonal
Purity Polyclonal antibodies are purified by peptide affinity chromatography
MW 23 kDa
Uniprot ID O95832 (Human); O88551 (Mouse); P56745 (Rat)
Entrez 9076
Product Description

CLDN1 (Claudin 1) is a Protein Coding gene. Diseases associated with CLDN1 include Ichthyosis, Leukocyte Vacuoles, Alopecia, And Sclerosing Cholangitis and Sclerosing Cholangitis. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration.GO annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is CLDN7.Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules.

Application Notes
Dilution Range IHC-P: 1:100-500, WB: 1:100-500 (based on 0.5mg/ml)
Validation Images
WB analysis of rat kidney (lane 1), mouse uterus (lane 2), mouse heart (lane 3), rat stomach (lane 4), rat thyroid (lane 5), rat lung (lane 6) using Claudin 1 antibody (2.5 ug/ml)
WB analysis of rat kidney (lane 1), mouse uterus (lane 2), mouse heart (lane 3), rat stomach (lane 4), rat thyroid (lane 5), rat lung (lane 6) using Claudin 1 antibody (2.5 ug/ml)
Immunohistochemical staining of paraffin embedded rat testis tissue using Claudin 1 antibody (2.5 ug/ml)
Immunohistochemical staining of paraffin embedded rat testis tissue using Claudin 1 antibody (2.5 ug/ml)
IHC-P staining of pig uterus tissue using Claudin 1 antibody (2.5 ug/ml)
IHC-P staining of pig uterus tissue using Claudin 1 antibody (2.5 ug/ml)
IHC-P image of mouse kidney tissue using anti-Claudin 1 (2.5 ug/ml)
IHC-P image of mouse kidney tissue using anti-Claudin 1 (2.5 ug/ml)
IHC-P staining of pig uterus tissue using Claudin 1 antibody (2.5 ug/ml)
IHC-P staining of pig uterus tissue using Claudin 1 antibody (2.5 ug/ml)
IHC-P staining of pig uterus tissue using Claudin 1 antibody (2.5 ug/ml)
IHC-P staining of pig uterus tissue using Claudin 1 antibody (2.5 ug/ml)
Western blot analysis of rat kidney (lane 1), mouse uterus (lane 2), mouse heart (lane 3), rat stomach (lane 4), rat thyroid (lane 5), rat lung (lane 6) using Claudin 1 antibody (2.5 ug/ml)
Western blot analysis of rat kidney (lane 1), mouse uterus (lane 2), mouse heart (lane 3), rat stomach (lane 4), rat thyroid (lane 5), rat lung (lane 6) using Claudin 1 antibody (2.5 ug/ml)
Immunohistochemical staining of pig uterus tissue using anti-Claudin 1 (2.5 ug/ml)
Immunohistochemical staining of pig uterus tissue using anti-Claudin 1 (2.5 ug/ml)
IHC-P staining of rat skin tissue using anti-Claudin 1 (2.5 ug/ml)
IHC-P staining of rat skin tissue using anti-Claudin 1 (2.5 ug/ml)
Immunohistochemical staining of pig uterus tissue using anti-Claudin 1 (2.5 ug/ml)
Immunohistochemical staining of pig uterus tissue using anti-Claudin 1 (2.5 ug/ml)
IHC-P image of pig uterus tissue using anti-Claudin 1 (2.5 ug/ml)
IHC-P image of pig uterus tissue using anti-Claudin 1 (2.5 ug/ml)
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