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Catalog Number | orb304274 |
---|---|
Category | Small Molecules |
Description | CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. |
CAS Number | [1188910-76-0] |
MW | 517.4572 |
SMILES | FC(C(C([H])([H])[H])(C([H])([H])[H])C1=C([H])C(N([H])C(N([H])C2C([H])=C([H])C([H])=C(C=2[H])OC2C3=C([H])C(=C(C([H])=C3N=C([H])N=2)OC([H])([H])[H])OC([H])([H])[H])=O)=NO1)(F)F |
Formula | C24H22F3N5O5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of CEP-32496
> 98%(HPLC) | |
1188910-76-0 |
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