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Catalog Number | orb341694 |
---|---|
Category | Small Molecules |
Description | CEP-32496 Hcl is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. |
CAS Number | [1227678-26-3] |
MW | 553.92 |
SMILES | O=C(NC1C=C(OC2N=CN=C3C=C(OC)C(OC)=CC=23)C=CC=1)NC1C=C(C(C(F)(F)F)(C)C)ON=1.[H]Cl |
Formula | C24H23ClF3N5O5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of CEP-32496 hydrochloride
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