CD86 antibody

• Catalog Number: orb66871
• Category: Antibodies
• Description: Rabbit polyclonal to CD86.T-lymphocyte activation antigen CD86 is a receptor involved in the costimulatory signal essential forT-lymphocyte proliferation and interleukin-2 production. CD86 binds to CD28 or CTLA-4 and may playa critical role in the early events of T-cell activation and costimulation of naive T-cells, such asdeciding between immunity and anergy. CD86 isoform 2 interferes with the formation of CD86 clusters,and thus acts as a negative regulator of T-cell activation.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: N-terminal region of human CD86
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 38
• UniProt ID: P42081
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-Activation B7 2gen antibody, anti-Activation
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Jurkat(Lane1) and mouse spleen(Lane2) using CD86 antibody