CD80 antibody

• Catalog Number: orb613916
• Category: Antibodies
• Description: Rabbit monoclonal antibody to CD80
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: IDEC-114 (Galiximab)
• Tested applications: Blocking, ELISA, FC, IHC, IP, WB
• Reactivity: Human
• Isotype: IgG
• Immunogen: Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: CD80
• UniProt ID: P33681
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: B7-1; T-lymphocyte activation antigen CD80; Activa
• Note: For research use only
• Application notes: Galiximab acts to decrease in cell proliferation, inhibition of the constitutively active NF-κB pathway, increase in apoptosis and ADCC against various B-cell lymphoma cell lines. Galiximb affects CD28 and CD152 interactions with CD80. This antibody can also be used for FC, WB, ELISA, IP and IHC.
• Expiration Date: 12 months from date of receipt.