CD49c Antibody (APC)

• Catalog Number: orb1881239
• Category: Antibodies
• Description: CD49c / Integrin alpha 3 is a type I transmembrane glycoprotein proteolytically cleaved into two disulfide linked chains. It noncovalently associates with CD29 (integrin beta 1) to form the VLA-3 complex, an adhesion receptor for extracellular matrix components (fibronectin, laminin 1, laminin 5, entactin, and collagen). It is expressed on adherent cells, mainly on fibroblasts, epithelial cells and endothelial cells.
• Clonality: Monoclonal
• Clone Number: ASC-1
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG1 kappa
• Immunogen: Human SSC-9 cell line (squamous cell carcinoma)
• Conjugation: APC
• Target: CD49c
• Entrez: 3675
• UniProt ID: P26006
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: ITGA3, VLA-3 alpha, FRP-2, FRP2, GAPB3
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.

Separation of HeLa cells stained using anti-human CD49c (ASC-1) APC antibody (10 μl reagent per million cells in 100 μl of cell suspension, red-filled) from HeLa cells stained using mouse IgG1 isotype control (MOPC-21) APC antibody (concentration in sample 1.67 μg/ml, same as CD49c APC concentration, black-dashed) in flow cytometry analysis (surface staining).