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Catalog Number | orb1821028 |
---|---|
Category | Antibodies |
Description | CD151, also known as PETA-3 (platelet-endothelial tetraspan antigen), is a four-pass transmembrane glycoprotein with short cytoplasmic N- and C-termini. CD151 is expressed mainly in platelets and megakaryocytes, immature hematopoietic cells, activated T cells, in endothelium, muscle cells, and epithelial cells. It associates with CD9, CD181, and integrin complexes alpha 3 / beta 1 (CD49c / CD29), alpha 5 / beta 1 (CD49e / CD29), and alpha 6 / beta 4 (CD49f / CD104). CD151 appears to be involved in cell adhesion and migration, including metastasis. |
Clonality | Monoclonal |
Clone Number | 50-6 |
Tested applications | FC |
Reactivity | Human |
Isotype | Mouse IgG1 kappa |
Immunogen | Human epidermoid carcinoma cell line Hep-3 |
Conjugation | APC |
Target | CD151 |
Entrez | 977 |
UniProt ID | P48509 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | RAPH blood group, MER2, SFA1, PETA-3, GP27 Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
Separation of human thrombocytes (red-filled) from CD151 negative neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD151 (50-6) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD151 (50-6) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
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