CD147 / Emmprin / Basigin Antibody

• Catalog Number: orb749798
• Category: Antibodies
• Description: CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: CB43
• Tested applications: FACS, IF
• Reactivity: Human
• Isotype: Mouse IgM, kappa
• Immunogen: Native human leukocytes were used as the immunogen for the Emmprin antibody.
• Dilution range: Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml
• Purity: PEG precipitation
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This Emmprin antibody is available for research use only.
• UniProt ID: P35613
• Storage: Store the Emmprin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the Emmprin antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.