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Catalog Number | orb1956320 |
---|---|
Category | Proteins |
Description | Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most abundantly expressed in articular chondrocytes and OA cartilage. |
Tag | N-His |
Purity | 98.00% |
UniProt ID | P0DP24 |
MW | 18.7 kDa (predicted); 19-22 kDa (reducing conditions) |
Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Expression System | E. coli |
Biological Origin | Human |
Biological Activity | Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most abundantly expressed in articular chondrocytes and OA cartilage. |
Expression Region | A DNA sequence encoding the mature form of human CALM2 (P0DP24) (Met1-Lys149) was expressed with a polyhistide tag at the N-terminus. Predicted N terminal: His |
Storage | -20°C |
Note | For research use only |
> 90% as determined by SDS-PAGE | |
20.4 kDa |