Calcineurin SubstRate peptide

SKU: orb216518

Description

Calcineurin SubstRate peptide

Images & Validation

• Application Notes:
  The 19-peptide DLDVPIPGRFDRRVSVAAE is a fragment of the RII subunit of the cAMP-dependent protein kinase. It is successfully used in a nonradioactive assay in which both phosphorylation by protein kinase and dephosphorylation by protein phosphatase 2B (calcineurin) are monitored by the simultaneous quantitative determination of phosphorylated and non-phosphorylated peptide using HPLC on an RP18 column with UV detection. This method allows the measurement of enzyme kinetics as well as the characterization of novel inhibitors.

Key Properties

• Source: Synthetic
• CAS Number: 113873-67-9
• MW: 2112.4
• Purity: > 95%
• Formula: C₉₂H₁₅₀N₂₈O₂₉
• Protein Sequence: Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu

Storage & Handling

• Storage: Shipped at 4°C. Store at -20°C for one year.
• Form/Appearance: Lyophilized powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of orb216518.