c-Myc

• Catalog Number: orb1945845
• Category: Antibodies
• Description: c-Myc is a phosphoprotein involved with cell proliferation and differentiation. It is a useful marker for differentiation between Burkitt's lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) since, despite morphological similarities between the two B-cell lymphomas, Anti-c-Myc stains all BL and only a few DLBCL cases. A panel of antibodies against c-Myc, CD10, BCL2, and Ki-67 is useful for cases where Myc FISH analysis is warranted or can be omitted. Nuclear c-Myc overexpression is common in luminal cells of prostate intraepithelial neoplasia, many primary carcinomas, and metastatic disease.
• Clonality: Monoclonal
• Species/Host: Rabbit
• Isotype: IgG
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and < 0.1% Sodium Azide
• Tested applications: IHC
• Clone Number: IHC448
• Storage: Store at 2-8°C. To ensure stability, immediately replace vial back in the refrigerator after each use
• Note: For research use only