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Catalog Number | orb66847 |
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Category | Antibodies |
Description | Rabbit polyclonal to BMI1.BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required tomaintain the transcriptionally repressive state of many genes, including Hox genes, throughoutdevelopment. PcG PRC1 complex acts via chromatin remodeling and modification of histones; itmediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in itsexpressibility. In the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligaseactivity of RNF2/RING2. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse |
Immunogen | C-terminal region of human BMI1 |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 37 |
UniProt ID | P35226 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-BMI1 antibody,anti-BMI1 antibody,anti-Bmi1 an Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of whole cell extracts from mouse brain using BMI1 antibody
ICC, IF, IHC-P, WB | |
Guinea pig, Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, IHC, WB | |
Canine, Human, Mouse, Porcine | |
Goat | |
Polyclonal | |
Unconjugated |
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