BMI1 Antibody

• Catalog Number: orb1731092
• Category: Antibodies
• Description: The polycomb group (PcG) of proteins contributes to the maintenance of cell identity, stem cell self-renewal, cell cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle arrest. PcG proteins exist in two complexes that cooperate to maintain long-term gene silencing through epigenetic chromatin modifications. The first complex, EED-EZH2, is recruited to genes by DNA-binding transcription factors and methylates histone H3 on Lys27.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Recombinant protein of human Bmi1
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 37 kDa; Observed MW: 43 kDa
• Entrez: 100532731
• UniProt ID: P35226
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: BMI1; PCGF4; RNF51; Polycomb complex protein BMI-1
• Note: For research use only
• Expiration Date: 12 months from date of receipt.