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BLBP Protein, Human, Recombinant
Catalog Number: orb1956425
| Catalog Number | orb1956425 |
|---|---|
| Category | Proteins |
| Description | BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives. |
| Tag | Tag Free |
| Purity | 98.00% |
| UniProt ID | O15540 |
| MW | 14.9 kDa (predicted); 16 kDa (reducing conditions) |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives. |
| Expression Region | A DNA sequence encoding the mature form of human FABP7 (O15540) (Met1-Ala132) was expressed. Predicted N terminal: Met |
| Storage | -20°C |
| Note | For research use only |
Human FABP7 protein [orb391701]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
E. coli
10 μg, 50 μg, 500 μgRecombinant Human FABP7 Protein, N-His [orb2833472]
> 90% as determined by SDS-PAGE.
17.05 kDa
100 μg, 50 μg, 20 μgHuman FABP7 protein [orb633317]
ELISA, WB
Greater than 95% by SDS-PAGE gel analyses
14.8 KDa
E.Coli
1 mg, 100 μg, 50 μg, 200 μgRecombinant Human FABP7 Protein, His Tag [orb1552448]
≥90% as determined by SDS-PAGE
This protein contains the human FABP7(Val2-Ala132) was fused with the N-terminus His Tag and expressed in E. coli.
100 μg, 50 μgRecombinant Human FABP7 Protein, His Tag [orb1551014]
> 95% by SDS-PAGE.
Recombinant Human FABP7 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Val2-Ala132) of human FABP7 (Accession #O15540) fused with a 6xHis Tag at the N-terminus.
50 μg
