beta-Amyloid-Protein [Pyr3] peptide

SKU: orb233741

Description

beta-Amyloid-Protein [Pyr3] peptide

Research Area

Neuroscience

Images & Validation

• Application Notes:
  [Pyr3]-Beta-Amyloid-Protein (3-42) was found to be the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. Therefore, [Pyr3]-Beta-Amyloid-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits. Nussbaum et al. studies the Prion-like behaviour and tau-dependent cytotoxicity of the truncated Aβ sequence.

Key Properties

• Source: Synthetic
• CAS Number: 183449-57-2
• MW: 4309.97
• Purity: > 95%
• Formula: C₁₉₆H₂₉₉N₅₃O₅₅S
• Protein Sequence: Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

Storage & Handling

• Storage: Shipped at 4°C. Store at -20°C for one year.
• Form/Appearance: Lyophilized powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of orb233741.