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Product Overview
Product Name BCL2 antibody
Catalog Number orb304038
Species/HostRabbit
ReactivityHuman, Mouse, Rat
Predicted Reactivity Bovine, Canine, Equine, Gallus, Guinea pig, Porcine
ConjugationUnconjugated
Custom conjugations
Tested applicationsELISA, IHC-P
Immunogen KLH conjugated synthetic peptide derived from human BCL2. Please contact us for the exact immunogen sequence. The peptide is available as orb374881.
Target BCL2
Alternative Names
Product Properties
Form/Appearance 10 mM PBS, 0.02% sodium azide
Concentration - 100 μg (in 200 μl): 0.5 mg/ml
- 200 μg (in 400 μl): 0.5 mg/ml
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Isotype IgG
ClonalityPolyclonal
Purity Polyclonal antibodies are purified by peptide affinity chromatography
Uniprot ID P10415 (Human); P10417 (Mouse); P49950 (Rat)
NCBI NP_000624.21; NM_000633.21
Entrez 596
Product Description

Rabbit polyclonal antibody to BCL2 also known as apoptosis regulator bcl2, which is expressed in the varieties of tissues but is highly expressed on the surface of ectocervix and coronary artery. It is found in the endoplasmic reticulum membrane. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells also regulates cell death by controlling the mitochondrial membrane permeability. This protein appears to function in a feedback loop system with caspases and can inhibit caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Application Notes
Dilution Range IHC-P: 1:50-200 (based on 0.5 mg/ml)
Validation Images
IHC-P image of rat bone marrow tissue using BCL2 antibody (2.5 ug/ml)
IHC-P image of rat bone marrow tissue using BCL2 antibody (2.5 ug/ml)
Immunohistochemical staining of paraffin embedded rat pancreas tissue using BCL2 antibody (2.5 ug/ml)
Immunohistochemical staining of paraffin embedded rat pancreas tissue using BCL2 antibody (2.5 ug/ml)
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