Bcl-2 Rabbit Polyclonal Antibody

SKU: orb100697

Description

Bcl-2 Rabbit Polyclonal Antibody

Research Area

Cell Biology

Images & Validation

• Tested Applications: FC, ICC
• Dilution Range: ICC/IF=1:100-500, Flow-Cyt=1μg/Test
• Reactivity: Human, Mouse
• Predicted Reactivity: Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human Bcl-2 (161-239/239aa)
• Target: BCL2
• Molecular Weight: 26 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bcl-2; PPP1R50; BCL2_HUMAN; BCL2; BCL2 apoptosis regulator; B-cell CLL/lymphoma 2; BCL2, apoptosis regulator; protein phosphatase 1, regulatory subunit 50

Quick Database Links

Gene Symbol

BCL2

UniProt

P10415

Mantawy, Eman M. et al. Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis Eur J Pharmacol, 728, 107-118 (2014)

PubMed: 24509133

Applications

IHC

Reactivity

Rat

Supriya Sharma, Pallavi Sharma, Pankaj Kulurkar, Damanpreet Singh, Dinesh Kumar, Vikram Patial Iridoid glycosides fraction from Picrorhiza kurroa attenuates cyclophosphamide-induced renal toxicity and peripheral neuropathy via PPAR-γ mediated inhibition of inflammation and apoptosis Phytomedicine, 36, 108–117 (2017)

PubMed: 29157803

Applications

IHC

Reactivity

Mouse

Haorong He 1 2, Yuanhang Wei 1 2, Yuqi Chen 1 2, Xiyu Zhao 1 2, Xiaoxu Shen 1 2, Qing Zhu 3 4, Huadong Yin High expression circRALGPS2 in atretic follicle induces chicken granulosa cell apoptosis and autophagy via encoding a new protein J Anim Sci Biotechnol., 15, 42 (2024)

PubMed: 38468340

Applications

IHC

Reactivity

Gallus

Mina Kiani 1, Malek Soleimani Mehranjani 2, Mohammad Ali Shariatzadeh Myoinositol improves sperm parameters in diabetic rats by reducing oxidative stress and regulating apoptosis-related genes J Mol Histol ., (2025)

PubMed: 40397159

Applications

IHC

Reactivity

Rat

Sara A. Wahdan, Mariane G. Tadros, Amani E. Khalifa RETRACTED ARTICLE: Antioxidant and antiapoptotic actions of selegiline protect against 3-NP-induced neurotoxicity in rats Naunyn-Schmiedeberg's Archives of Pharmacology, 390, 9 (2017)

PubMed: 28643087

Applications

IHC

Reactivity

Rat

Tomar, Ameesha et al. The dietary isoflavone daidzein mitigates oxidative stress, apoptosis, and inflammation in CDDP-induced kidney injury in rats: Impact of the MAPK signaling pathway J Biochem Mol Toxicol, 34, e22431 (2020)

PubMed: 31833131

Applications

IHC

Reactivity

Rat

Mahdy, Heba M. et al. The anti-apoptotic and anti-inflammatory properties of puerarin attenuate 3-nitropropionic-acid induced neurotoxicity in rats Can J Physiol Pharmacol, 92, 252-258 (2014)

PubMed: 24593790

Reactivity

Rat