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BAFF Antibody / BLyS
Catalog Number: orb385959
| Catalog Number | orb385959 |
|---|---|
| Category | Antibodies |
| Description | BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). |
| Clonality | Monoclonal |
| Species/Host | Mouse |
| Isotype | Mouse IgG1, kappa |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant human BAFF protein was used as the immunogen for this BAFF antibody. |
| UniProt ID | Q9Y275 |
| Tested applications | ELISA |
| Dilution range | ELISA (order BSA/sodium azide-free format for coating) |
| Application notes | Optimal dilution of the Campylobacter jejuni antibody should be determined by the researcher. |
| Antibody Type | Primary Antibody |
| Clone Number | C257/1638 |
| Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Hazard Information | This BAFF antibody is available for research use only. |
| Note | For research use only |
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