Aquaporin 4 Antibody

• Catalog Number: orb1906390
• Category: Antibodies
• Description: Aquaporin 4 Antibody
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: C9401
• Tested applications: ELISA, FA, FC, IP
• Reactivity: Human
• Isotype: IgG2b
• Immunogen: The original antibody was generated by immunizing an aquaporin 4 knock out mice with human AQP4 as an immunogen expressed on the surface of baculovirus.
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: Aquaporin 4
• UniProt ID: P55087
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: AQP4; AQP-4; Aquaporin-4; MIWC; WCH4; Mercurial-in
• Note: For research use only
• Application notes: This antibody binds extracellular domain of human aquaporin 4 with a very high binding affinity. The binding of this antibody inhibits the binding of NMO-IgG to AQP4 (PMID: 23746426). The binding affinity of this antibody for human AQP4 M23 isoform expressed on the surface of baculovirus and CHO cells was tested with ELISA (PMID: 26398585; WO2014196658). The binding characterization of this antibody was done using flow cytometry. This antibody can be used for the immunoprecipitation of human AQP4 but not mouse AQP4 (WO2014196658; PMID: 23909421). This antibody is not suitable for detection of denatured human AQP4 in a western blot assay (WO2014196658).
• Expiration Date: 12 months from date of receipt.