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APOBEC3g (N) Antibody, Rabbit Polyclonal

Catalog Number: orb67157

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$ 440.00
Catalog Numberorb67157
CategoryAntibodies
DescriptionRabbit polyclonal to APOBEC3 gamma.DNA dC-dU-editing enzyme APOBEC-3G (APOBEC3G) belongs to the cytidine and deoxycytidylatedeaminase family. It is a DNA deaminase (cytidine deaminase) that mediates a form of innateresistance to retroviral infections (at least to HIV-1 infection) by triggering G-to-A hypermutation in thenewly synthesized viral DNA. The inhibition of viral replication is either due to the degradation of theminus strand before its integration or to the lethality of the hypermutations. APOBEC3G also inhibitsthe infectivity of retroviral particles only distantly related to HIV-1, such as the simianimmunodeficiency virus (SIV), the equine infectious anemia virus (EIAV) and the murine leukemiavirus (MLV).
Species/HostRabbit
ClonalityPolyclonal
Tested applicationsWB
ReactivityHuman
ImmunogenN-terminal region of human APOBEC3G
Dilution rangeWB:1:500-1:1000
PurityAffinity purification
ConjugationUnconjugated
MW46
UniProt IDQ9HC16
Storage-20°C
Buffer/Preservatives0.01% NaN3
Alternative namesanti-APOBEC3 gamma antibody,anti-DNA dCGreater tha
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NoteFor research use only
Expiration Date12 months from date of receipt.
APOBEC3g (N) Antibody, Rabbit Polyclonal

Western blot of total cell extracts from human Jurkat using APOBEC3 gamma antibody