Anti-TNFSF7 / CD27L / CD70 Reference Antibody (vorsetuzumab)

• Catalog Number: orb1818390
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Tested applications: ELISA, FC
• Reactivity: Human
• Isotype: IgG1
• Antibody Type: Primary Antibody
• Concentration: 1mg/ml
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Conjugation: Unconjugated
• MW: 146.1
• UniProt ID: P32970
• Protein Sequence: TNFSF7 / CD27L / CD70
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

The purity of Anti-TNFSF7 / CD27L / CD70 Reference Antibody (vorsetuzumab) is more than 99.29%, determined by SEC-HPLC.

The endocytosis ratio vorsetuzumab by 786-O increased with the increase of antibody concentration, and the Internalization Rate (%) reached 55% at antibody concentration of 0.67 nM.

Anti-TNFSF7 / CD27L / CD70 Reference Antibody (vorsetuzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

HL-60 cells were stained with Anti-TNFSF7 / CD27L / CD70 Reference Antibody (vorsetuzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC150=0.06731 ug/mL