Anti-OSMR Reference Antibody (vixarelimab)

• Catalog Number: orb1818286
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Tested applications: ELISA, FC
• Reactivity: Human, Monkey
• Isotype: IgG4SP
• Antibody Type: Primary Antibody
• Concentration: 1mg/ml
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Conjugation: Unconjugated
• MW: 145 Da
• UniProt ID: Q99650
• Protein Sequence: OSMR
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: Oncostatin-M-specific receptor subunit beta, Inter
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

The purity of Anti-OSMR Reference Antibody (vixarelimab) is more than 96.9%, determined by SEC-HPLC.

Immobilized human OSMR His at 2 µg/mL can bind Anti-OSMR Reference Antibody (vixarelimab), EC50=0.0024 µg/mL

Anti-OSMR Reference Antibody (vixarelimab) P-STAT3 Assay was evaluated using NHDF. The IC50 was approximately 0.3493 nM.

Anti-OSMR Reference Antibody (vixarelimab).MCP-1 secretion was evaluated using NHDF. The IC50 was approximately 0.0812 nM.

Anti-OSMR Reference Antibody (vixarelimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

Human OSMR HEK293 cells were stained with Anti-OSMR Reference Antibody (vixarelimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC261=0.0359 µg/mL