MRP1/ABCC1 Antibody

SKU: orb76148

Description

MRP1/ABCC1 Antibody

Research Area

Cancer Biology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

• Tested Applications: IHC, WB
• Dilution range: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MRP1, different from the related rat and mouse sequences by one amino acid.
• Target: Multidrug resistance-associated protein 1
• Molecular Weight: 29 kDa
• Purification: Immunogen affinity purified.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Lyophilized
• Buffer/Preservatives: Each vial contains 5mg rAlbumin, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Disclaimer: For research use only

Alternative Names

Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Leukotriene C (4) transporter; LTC4 transporter; ABCC1; MRP, MRP1

Western blot analysis of Lane 1: JURKAT Cell Lysate, Lane 2: CEM Cell Lysate, Lane 3: A549 Cell Lysate using ABCC1 antibody

Immunohistochemical analysis of formalin-fixed paraffin embedded Human Lung Cancer Tissue using ABCC1 antibody

Quick Database Links

Gene Symbol

Multidrug resistance-associated protein 1

UniProt

P33527

References

Mo, Lihong et al. Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells PLoS One, 10, e0131579 (2015)

PubMed: 26148191