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| Catalog Number | orb2321165 |
|---|---|
| Category | Antibodies |
| Description | NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells. |
| Target | NKp80 |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 kappa |
| Conjugation | APC |
| Reactivity | Human, Monkey |
| Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Immunogen | recombinant human NKp80 extracellular domain |
| UniProt ID | Q9NZS2 |
| Tested applications | FC |
| Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Clone Number | 5D12 |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Alternative names | KLRF1, CLEC5C |
| Note | For research use only |
| Entrez | 51348 |
| Expiration Date | 12 months from date of receipt. |
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