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Item 1 of 3
HGFR/c-Met Antibody (MMAE)
Catalog Number: orb1805476
| Catalog Number | orb1805476 |
|---|---|
| Category | Antibodies |
| Description | Anti-HGFR / c-Met Reference Antibodydy and Monomethyl auristatin E (MMAE) that has recently obtained the breakthrough therapy designation (BTD) for the treatment of patients with c-Met overexpression, advanced/metastatic wild-type (WT) epithelial growth factor receptor (EGFR) non-squamous non-small cell lung cancer (sqNSCLC) that progressed during or after platinum-based chemotherapy. |
| Target | HGFR / c-Met |
| Clonality | Recombinant |
| Conjugation | MMAE |
| Reactivity | Human |
| Concentration | 1 mg/mL |
| Buffer/Preservatives | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Purity | > 95% |
| Purification | Protein A |
| UniProt ID | P08581 |
| MW | 151.37 kDa |
| Tested applications | ELISA, FA, FACS, In vivo |
| Antibody Type | Recombinant Antibody |
| Expression System | CHO |
| Endotoxins | < 0.001 EU/ug |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Note | For research use only |
Anti-HGFR / c-Met Reference Antibody (telisotuzumab vedotin) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-HGFR / c-Met Reference Antibody (telisotuzumab vedotin)is more than 95% ;determined by SEC-HPLC.
Immobilized human cMet His at 2 μg/mL can bind Anti-HGFR / c-Met Reference Antibody (telisotuzumab vedotin);EC50=0.105μg/mL.
