Anti-CSF2Rb / CD131 Reference Antibody (CSL311)

• Catalog Number: orb1818425
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Tested applications: ELISA, FC
• Reactivity: Human
• Isotype: IgG4
• Antibody Type: Primary Antibody
• Concentration: 1mg/ml
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Conjugation: Unconjugated
• MW: 144.66
• UniProt ID: P32927
• Protein Sequence: CSF2Rb / CD131
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: Cytokine receptor common subunit beta, CDw131, GM-
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

IL-3-mediated proliferation of TF-1 can be completely blocked by antibodies with an IC50 of 0.2109 nM.

GM-CSF-mediated proliferation of TF-1 can be completely blocked by antibodies with an IC50 of 4.105 nM.

The purity of Anti-CSF2Rb / CD131 Reference Antibody (CSL311) is more than 98.34%, determined by SEC-HPLC.

Immobilized human CSF2RB His at 2 µg/mL can bind Anti-CSF2Rb / CD131 Reference Antibody (CSL311), EC50=0.0122 µg/mL

Anti-CSF2Rb / CD131 Reference Antibody (CSL311) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

Human CSF2RB HEK293 cells were stained with Anti-CSF2Rb / CD131 Reference Antibody (CSL311) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC114=0.049 µg/mL